PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33841136-13 2021 Moreover, alternol increased the level of CHOP, which is necessary for the enhancing effect of alternol on TRAIL-induced apoptosis, given that downregulation of CHOP abrogated the synergistic effect. Alternol 95-103 DNA damage inducible transcript 3 Homo sapiens 42-46 33841136-13 2021 Moreover, alternol increased the level of CHOP, which is necessary for the enhancing effect of alternol on TRAIL-induced apoptosis, given that downregulation of CHOP abrogated the synergistic effect. Alternol 10-18 DNA damage inducible transcript 3 Homo sapiens 42-46 33841136-16 2021 Conclusion: Taken together, our research suggested that alternol increased TRAIL-mediated apoptosis via inhibiting antiapoptotic proteins and upregulating DR5 levels via ROS generation and the CHOP pathway. Alternol 56-64 DNA damage inducible transcript 3 Homo sapiens 193-197