PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30400936-11	2018	The molecular docking showed that licochalcone a and beta-sitosterol can closely bind two targets (BCL2 and PRKCA) that involved in EGFR-TKI resistance pathway.	licochalcone A	34-48	epidermal growth factor receptor	Homo sapiens	132-136	
33645088-6	2021	Molecular docking results showed that licochalcone A,(Z)-3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxy-phenyl) ethyl] acrylamide, consumeclose grain successfully docked with the key target EGFR, and binding energy of the three compounds was less than-5 kcal mol~(-1).	licochalcone A	38-52	epidermal growth factor receptor	Homo sapiens	189-193	
33247550-0	2021	Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells.	licochalcone A	0-14	epidermal growth factor receptor	Homo sapiens	24-28	
33247550-2	2021	Here, we reported the natural product, licochalcone A, exhibited a profound anti-tumour efficacy through directly targeting EGFR signalling.	licochalcone A	39-53	epidermal growth factor receptor	Homo sapiens	124-128	
33247550-3	2021	Licochalcone A inhibited in vitro cell growth, colony formation and in vivo tumour growth of either wild-type (WT) or activating mutation EGFR-expressed NSCLC cells.	licochalcone A	0-14	epidermal growth factor receptor	Homo sapiens	138-142	
33247550-4	2021	Licochalcone A bound with L858R single-site mutation, exon 19 deletion, L858R/T790M mutation and WT EGFR ex vivo, and impaired EGFR kinase activity both in vitro and in NSCLC cells.	licochalcone A	0-14	epidermal growth factor receptor	Homo sapiens	100-104	
33247550-4	2021	Licochalcone A bound with L858R single-site mutation, exon 19 deletion, L858R/T790M mutation and WT EGFR ex vivo, and impaired EGFR kinase activity both in vitro and in NSCLC cells.	licochalcone A	0-14	epidermal growth factor receptor	Homo sapiens	127-131	
33247550-7	2021	Mechanistically, we found that treatment with licochalcone A translationally suppressed survivin through inhibiting EGFR downstream kinases ERK1/2 and Akt.	licochalcone A	46-60	epidermal growth factor receptor	Homo sapiens	116-120