PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28704925-0	2017	Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCgamma2-PKC, Akt, and MAPK Pathways.	licochalcone A	0-14	thymoma viral proto-oncogene 1	Mus musculus	108-111	
26576227-0	2015	Lico A Enhances Nrf2-Mediated Defense Mechanisms against t-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells.	licochalcone A	0-6	thymoma viral proto-oncogene 1	Mus musculus	107-110	
26576227-5	2015	Lico A also obviously induced the activation of serine/threonine kinase (Akt) and extracellular signal-regulated kinase (ERK), but PI3K/Akt and ERK inhibitors treatment displayed clearly decreased levels of LicoA-induced Nrf2 nuclear translocation and HO-1 expression, respectively.	licochalcone A	0-6	thymoma viral proto-oncogene 1	Mus musculus	73-76	
26576227-6	2015	Furthermore, Lico A treatment markedly attenuated t-BHP-induced oxidative damage, which was reduced by treatment with PI3K/Akt, ERK, and HO-1 inhibitors.	licochalcone A	13-19	thymoma viral proto-oncogene 1	Mus musculus	123-126	
26576227-7	2015	Therefore, Lico A might have a protective role against t-BHP-induced cytotoxicity by modulating HO-1 and by scavenging ROS via the activation of the PI3K/Akt and ERK/Nrf2 signaling pathways.	licochalcone A	11-17	thymoma viral proto-oncogene 1	Mus musculus	154-157