PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25572524-0	2015	Licochalcone-A induces intrinsic and extrinsic apoptosis via ERK1/2 and p38 phosphorylation-mediated TRAIL expression in head and neck squamous carcinoma FaDu cells.	licochalcone A	0-14	mitogen-activated protein kinase 1	Homo sapiens	72-75	
25572524-8	2015	Lico-A-induced TRAIL expression was mediated in part by a MAPK signaling pathway involving ERK1/2 and p38.	licochalcone A	0-6	mitogen-activated protein kinase 1	Homo sapiens	102-105	
33447049-0	2020	ERK Activation-Mediated Autophagy Induction Resists Licochalcone A-Induced Anticancer Activities in Lung Cancer Cells in vitro.	licochalcone A	52-66	mitogen-activated protein kinase 1	Homo sapiens	0-3	
34988084-6	2021	Molecular docking showed that two core active components, quercetin and licochalcone A, exhibited the highest component-like properties (DL), and could bind well to CDK1 and MAPK1 protein.	licochalcone A	72-86	mitogen-activated protein kinase 1	Homo sapiens	174-179	
34988084-7	2021	The experimental validation of these two components showed that quercetin inhibited cell growth through CDK1 dephosphorylation-mediated cell cycle arrest at G2/M phase in human AML U937 and HL60 cells, and licochalcone A induced cell differentiation in these leukemia cells via activation of MAPK1 and upregulation of CD11b.	licochalcone A	206-220	mitogen-activated protein kinase 1	Homo sapiens	292-297	
21468757-10	2012	In summary, licochalcone A induced osteoblast differentiation with ERK activation in both MC4 and C2C12 cells and it exhibited in vivo osteogenic activity in zebrafish skeletal development and mouse calvarial bone formation.	licochalcone A	12-26	mitogen-activated protein kinase 1	Homo sapiens	67-70	
30465574-0	2018	Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways.	licochalcone A	0-14	mitogen-activated protein kinase 1	Homo sapiens	90-93	
29730172-0	2018	Glycyrrhiza flavonoids and its major component, licochalcone A, inhibit melanogenesis through MAPK/ERK pathway by activating ERK phosphorylation.	licochalcone A	48-62	mitogen-activated protein kinase 1	Homo sapiens	94-98	
29730172-0	2018	Glycyrrhiza flavonoids and its major component, licochalcone A, inhibit melanogenesis through MAPK/ERK pathway by activating ERK phosphorylation.	licochalcone A	48-62	mitogen-activated protein kinase 1	Homo sapiens	99-102	
29730172-0	2018	Glycyrrhiza flavonoids and its major component, licochalcone A, inhibit melanogenesis through MAPK/ERK pathway by activating ERK phosphorylation.	licochalcone A	48-62	mitogen-activated protein kinase 1	Homo sapiens	125-128	
30983163-0	2019	Licochalcone A induces apoptotic cell death via JNK/p38 activation in human nasopharyngeal carcinoma cells.	licochalcone A	0-14	mitogen-activated protein kinase 1	Homo sapiens	52-55