PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31303993-5 2019 We find that installing and oxidizing the C17 methylsulfide prior to reducing the C15 ketone provides the greatest yield of the desired C15,C16 diastereomer. Ketones 86-92 cytokine like 1 Homo sapiens 42-45 23583279-6 2014 An increasing trend was demonstrated with advancing gestation toward the production of ketones (and 3beta-hydroxyl groups in the case of 3alpha-hydroxy-steroids) was demonstrated in the fetus on the expense of 3alpha-hydroxy-, 17beta-hydroxy-, and 20alpha-hydroxy-groups weakening in the sequence C17, C3, and C20. Ketones 87-94 cytokine like 1 Homo sapiens 297-300 22481539-2 2012 It has been observed that converting stevioside and rebaudioside A to their corresponding ketones by switching the doubly bonded methylene on C-17 for a ketone group actually removes the sweet taste properties of these molecules completely. Ketones 90-97 cytokine like 1 Homo sapiens 142-146 22481539-2 2012 It has been observed that converting stevioside and rebaudioside A to their corresponding ketones by switching the doubly bonded methylene on C-17 for a ketone group actually removes the sweet taste properties of these molecules completely. Ketones 90-96 cytokine like 1 Homo sapiens 142-146 21472158-3 2011 A Lewis-acid mediated allylation of the resulting acetal at C13 and a Horner-Wadsworth-Emmons olefination on the ketone at C17 complete the synthesis. Ketones 113-119 cytokine like 1 Homo sapiens 123-126 19702782-2 2009 One of the crucial interactions may be between the C20 ketone group (D-ring substituent at C17) of the neurosteroid, and the N407 and Y410 residues in the M4 domain of the receptor. Ketones 55-61 cytokine like 1 Homo sapiens 91-94 11667606-5 1996 Irradiation of the diketone, 6beta-(DPSO)-5beta-androstane-3,17-dione (5), gives two ring D-derived photoproducts, an epimer (19) and an enal (18), both coming from the C17 ketone excited singlet state. Ketones 21-27 cytokine like 1 Homo sapiens 169-172 11667606-8 1996 6.5 x 10(9) s(-)(1), with the chemistry indicative of facile intra-SSET between the C3 and C17 ketones. Ketones 95-102 cytokine like 1 Homo sapiens 91-94 1504919-4 1992 Amino acid sequence analyses show that human 17 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C17 on estrogens and androgens, and rat 11 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C11 of glucocorticoids, and Rhizobium meliloti NodG and Bradyrhizobium japonicum. Ketones 138-144 cytokine like 1 Homo sapiens 148-151 1504919-4 1992 Amino acid sequence analyses show that human 17 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C17 on estrogens and androgens, and rat 11 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C11 of glucocorticoids, and Rhizobium meliloti NodG and Bradyrhizobium japonicum. Ketones 281-287 cytokine like 1 Homo sapiens 148-151 970695-4 1976 It catalyses the transformation into ketone of the secondary alcohol group at the 3 beta position of sterols which possess in the C17 position a lateral chain of at least two carbon atoms. Ketones 37-43 cytokine like 1 Homo sapiens 130-133