PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29364494-0 2018 Oxcarbazepine causes neurocyte apoptosis and developing brain damage by triggering Bax/Bcl-2 signaling pathway mediated caspase 3 activation in neonatal rats. Oxcarbazepine 0-13 BCL2 associated X, apoptosis regulator Rattus norvegicus 83-86 29364494-13 2018 OXC 281.25 mg/kg and OXC 375 mg/kg significantly increased Bax, Bax/Bcl-2 ratio and cytochrome C release in frontal lobes compared to Control group in P5 rats (p<0.05). Oxcarbazepine 0-3 BCL2 associated X, apoptosis regulator Rattus norvegicus 59-62 29364494-13 2018 OXC 281.25 mg/kg and OXC 375 mg/kg significantly increased Bax, Bax/Bcl-2 ratio and cytochrome C release in frontal lobes compared to Control group in P5 rats (p<0.05). Oxcarbazepine 0-3 BCL2 associated X, apoptosis regulator Rattus norvegicus 64-67 29364494-13 2018 OXC 281.25 mg/kg and OXC 375 mg/kg significantly increased Bax, Bax/Bcl-2 ratio and cytochrome C release in frontal lobes compared to Control group in P5 rats (p<0.05). Oxcarbazepine 21-24 BCL2 associated X, apoptosis regulator Rattus norvegicus 59-62 29364494-13 2018 OXC 281.25 mg/kg and OXC 375 mg/kg significantly increased Bax, Bax/Bcl-2 ratio and cytochrome C release in frontal lobes compared to Control group in P5 rats (p<0.05). Oxcarbazepine 21-24 BCL2 associated X, apoptosis regulator Rattus norvegicus 64-67 29364494-14 2018 CONCLUSIONS: Oxcarbazepine at a concentration of 281.25 mg/kg or more causes neurocyte apoptosis and developing brain damage by triggering Bax/Bcl-2 signaling pathway mediated caspase 3 activation in neonatal rats. Oxcarbazepine 13-26 BCL2 associated X, apoptosis regulator Rattus norvegicus 139-142