PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16928788-4	2006	In liver, PCN induced the expression of Oatp1a4 and Mrp3 mRNA in wild-type (WT) mouse liver, but not in PXR-null mice.	Pregnenolone Carbonitrile	10-13	prolactin family 2, subfamily c, member 4	Mus musculus	52-56	
17435798-6	2007	Compared to CA alone, co-administration of PCN to CA-fed PXR+/+ mice significantly decreased hepatotoxicity and was associated with induction of MRP3 mRNA as well as CYP3A11 mRNA and functional activity.	Pregnenolone Carbonitrile	43-46	prolactin family 2, subfamily c, member 4	Mus musculus	145-149	
17435798-8	2007	CONCLUSIONS: Protection of PXR+/+ mice against CA-induced hepatotoxicity by PCN is associated with the induction of MRP3 and CYP3A11 expression.	Pregnenolone Carbonitrile	76-79	prolactin family 2, subfamily c, member 4	Mus musculus	116-120	
16928788-8	2006	Therefore, PCN regulates the expression of some transporters, namely, Oatp1a4 and Mrp3 in liver, as well as Abca1, Cnt2, Mdr1a, and Mrp2 in small intestine via a PXR-mediated mechanism.	Pregnenolone Carbonitrile	11-14	prolactin family 2, subfamily c, member 4	Mus musculus	82-86