PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22461452-4 2012 The weight of evidence from these studies supported a novel MoA where sulfoxaflor is an agonist to the fetal, but not adult, rat muscle nAChR and that prolonged agonism on this receptor in fetal/neonatal rats causes sustained striated muscle contracture resulting in concomitant reduction in muscle responsiveness to physiological nerve stimulation. sulfoxaflor 70-81 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 136-141 22461452-7 2012 Taken together, the data support the hypothesis that the developmental effects of sulfoxaflor in rats are mediated via sustained agonism on the fetal muscle nAChR during late fetal development and are considered not relevant to humans. sulfoxaflor 82-93 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 157-162