PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31809762-6 2020 The results revealed that treatment with GW9508 could significantly ameliorate cognitive deficits of APP/PS1 mice, upregulate the expression levels of cAMP, p-CREB and neurotrophic factors in vivo, while GW9508 also ameliorate Abeta1-42-induced neuron damage and downregulate the expression levels of pathological protein such as p-JNK, JNK and apoptosis-related proteins such as IL-6, IL-1beta, TNF-alpha and caspase-3 in vitro. GW9508 41-47 amyloid beta (A4) precursor protein Mus musculus 101-108