PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34275493-12	2021	GW9508 upregulated the phosphorylation of PAK4, CREB, and protein level of KDM6B, CD206, IL-10, which was also met with the downregulation of inflammatory markers IL-1beta and TNF-alpha.	GW9508	0-6	interleukin 10	Rattus norvegicus	89-94	
30981281-10	2019	GW9508 also markedly stimulated gene and protein expression of IL-10 and beta-endorphin in cultured primary spinal microglia and astrocytes but not in neurons, originated from 1-day-old neonatal rats.	GW9508	0-6	interleukin 10	Rattus norvegicus	63-68	
30981281-9	2019	Intrathecal GW9508 significantly enhanced IL-10 and beta-endorphin immunostaining in spinal microglia and astrocytes but not in neurons.	GW9508	12-18	interleukin 10	Rattus norvegicus	42-47	
30981281-11	2019	The IL-10 antibody inhibited GW9508-stimulated gene expression of the beta-endorphin precursor proopiomelanocortin (POMC) but not IL-10, whereas the beta-endorphin antibody did not affect GW9508-stimulated IL-10 or POMC gene expression.	GW9508	29-35	interleukin 10	Rattus norvegicus	4-9	
30981281-11	2019	The IL-10 antibody inhibited GW9508-stimulated gene expression of the beta-endorphin precursor proopiomelanocortin (POMC) but not IL-10, whereas the beta-endorphin antibody did not affect GW9508-stimulated IL-10 or POMC gene expression.	GW9508	188-194	interleukin 10	Rattus norvegicus	4-9	
30981281-12	2019	GW9508 increased phosphorylation of mitogen-activated protein kinases (MAPKs) including p38, extracellular signal-regulated kinase (ERK), and c-Jun N-terminal kinase (JNK), and its stimulatory effects on IL-10 and POMC expression were blocked by each MAPK isoform inhibitor.	GW9508	0-6	interleukin 10	Rattus norvegicus	204-209	
30981281-13	2019	Spinal GW9508-induced mechanical antiallodynia was completely blocked by intrathecal minocycline, IL-10 neutralizing antibody, beta-endorphin antiserum, and mu-opioid receptor-preferred antagonist naloxone.	GW9508	7-13	interleukin 10	Rattus norvegicus	98-103