PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26304690-0 2016 Investigation on the interaction of cefpirome sulfate with lysozyme by fluorescence quenching spectroscopy and synchronous fluorescence spectroscopy. cefpirome 36-53 lysozyme Homo sapiens 59-67 26304690-1 2016 The reaction mechanism of cefpirome sulfate with lysozyme at different temperatures (298, 310 and 318 K) was investigated using fluorescence quenching and synchronous fluorescence spectroscopy under simulated physiological conditions. cefpirome 26-43 lysozyme Homo sapiens 49-57 26304690-2 2016 The results clearly demonstrated that cefpirome sulfate caused strong quenching of the fluorescence of lysozyme by a static quenching mechanism. cefpirome 38-55 lysozyme Homo sapiens 103-111 26304690-4 2016 Static electric forces played a key role in the interaction between cefpirome sulfate and lysozyme, and the number of binding sites in the interaction was close to 1. cefpirome 68-85 lysozyme Homo sapiens 90-98 26304690-8 2016 In addition, the effect of cefpirome sulfate on the secondary structure of lysozyme was analyzed using circular dichroism spectroscopy. cefpirome 27-44 lysozyme Homo sapiens 75-83