PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27646854-4 2016 Guadecitabine is formulated as a dinucleotide of decitabine and deoxyguanosine that is resistant to cytidine deaminase (CDA) degradation and results in prolonged in vivo exposure to decitabine following small volume subcutaneous administration of guadecitabine. guadecitabine 0-13 cytidine deaminase Homo sapiens 100-118 27646854-4 2016 Guadecitabine is formulated as a dinucleotide of decitabine and deoxyguanosine that is resistant to cytidine deaminase (CDA) degradation and results in prolonged in vivo exposure to decitabine following small volume subcutaneous administration of guadecitabine. guadecitabine 0-13 cytidine deaminase Homo sapiens 120-123 27646854-11 2016 Guadecitabine, in contrast to decitabine, blocked growth in HCC cells overexpressing macroH2A1 histones and with high CDA levels, despite being unable to fully demethylate CDKN2A, RUNX3, and DLEC1 promoters altered by macroH2A1. guadecitabine 0-13 cytidine deaminase Homo sapiens 118-121 26296954-2 2015 Guadecitabine (SGI-110) is a novel hypomethylating dinucleotide of decitabine and deoxyguanosine resistant to degradation by cytidine deaminase. guadecitabine 0-13 cytidine deaminase Homo sapiens 125-143