PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33628297-13 2021 The levels of Nrf2, HO-1, NQO1, and PTEN were upregulated by SMS in rat synovial tissues. sms 61-64 phosphatase and tensin homolog Rattus norvegicus 36-40 33628297-14 2021 Conclusions: This study demonstrated that SMS effectively alleviated the disease progression of CIA by decreasing the levels of proinflammatory cytokines and reducing oxidative stress damage, as indicated by IL-6, TNF-alpha, COX-2, and PGE2 levels; inhibiting the overproduction of MDA and MPO; and enhancing antioxidant enzymes by upregulating the Nrf2/ARE/PTEN signalling pathway. sms 42-45 phosphatase and tensin homolog Rattus norvegicus 358-362