PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15311153-8 2004 Plasmin generation in the presence of variant fibrinogens was similar, although not identical, to normal, and plasmin generation in the presence of variant fibrins was impaired for the Asp to Ala variants. Aspartic Acid 185-188 plasminogen Homo sapiens 110-117 10613648-10 1999 These data indicate that residue Asp 318 is important for normal fibrin polymerization and the protective effect of calcium ions against plasmin degradation of the C-terminal part of the gamma-chain. Aspartic Acid 33-36 plasminogen Homo sapiens 137-144 15269832-5 2004 Analysis of 24 healthy subjects showed that subjects with the most common IEF plg phenotype A (n=12) were homozygous for aspartate at position 453 (453D), while both subjects with IEF plg phenotype B were homozygous for asparagine at this position (453N). Aspartic Acid 121-130 plasminogen Homo sapiens 78-81 9761475-14 1998 Within the Cys34-Cys42 loop of L-NTP, the structure of the Glu-Glu-Asp-Glu-Glu39 segment appears to be relatively less defined, as is the case for the stretch containing Lys5O within the Cys42-Cys54 segment, consistent with the latter possibly interacting with kringle domains in intact Glul-Pgn. Aspartic Acid 67-70 plasminogen Homo sapiens 292-295 8506386-3 1993 After activation of this zymogen to its corresponding form of the serine protease plasmin (MrhPm), this latter enzyme was essentially inactive toward an amide plasmin substrate, most likely from alteration of the spatial relationships of the active-site His-603 to its partners of the catalytic triad, Asp-646 and Ser-741. Aspartic Acid 302-305 plasminogen Homo sapiens 82-89 1382726-7 1992 Peptides from plasmin digestion of fibronectin containing cell attachment site with sequence Arg-Gly-Asp-Ser and also synthetic peptide reproducing this amino-acid sequence at the concentration of 1000 micrograms/ml released about 50% of collagenase and 55% of elastase from PMN-leukocytes. Aspartic Acid 101-104 plasminogen Homo sapiens 14-21 40605-5 1979 It is suggested that the catalytically essential ionizing group of plasmin having a pK of 8.4 is the alpha-ammonium group of the NH2-terminal Val-561 or the light chain of plasmin, forming an ion pair with a COO- group of an aspartate or glutamate residue. Aspartic Acid 225-234 plasminogen Homo sapiens 67-74 40605-5 1979 It is suggested that the catalytically essential ionizing group of plasmin having a pK of 8.4 is the alpha-ammonium group of the NH2-terminal Val-561 or the light chain of plasmin, forming an ion pair with a COO- group of an aspartate or glutamate residue. Aspartic Acid 225-234 plasminogen Homo sapiens 172-179