PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20385109-5 2010 A very recent report has identified Nat8l as the gene encoding Asp-NAT and confirmed that the only child diagnosed with a lack of NAA on brain magnetic resonance spectrograms has a 19-bp deletion in this gene. Aspartic Acid 63-66 N-acetyltransferase 8 like Homo sapiens 36-41 32639720-1 2020 We report the results of computational modeling of a three-dimensional all-atom structure of the membrane-associated protein encoded by the NAT8L gene, aspartate N-acetyltransferase, which is essential for brain synthesis of N-acetyl-L-aspartate (NAA). Aspartic Acid 152-161 N-acetyltransferase 8 like Homo sapiens 140-145 32639720-3 2020 We apply a computational protocol employing the contact map prediction, ab initio folding, homology modeling and refinement to obtain a structure of NAT8L with the aspartate and acetyl coenzyme A cofactors in the protein molecule. Aspartic Acid 164-173 N-acetyltransferase 8 like Homo sapiens 149-154 30595160-3 2019 Aspartate N-acetyltransferase (Asp-NAT, encoded by Nat8l) synthesizes NAA from acetyl-CoA and aspartate and increases energy expenditure in brown adipocytes. Aspartic Acid 94-103 N-acetyltransferase 8 like Homo sapiens 51-56 20385109-7 2010 In studies done concurrently in our laboratory we have demonstrated via cloning, expression, specificity for acetylation of aspartate, responsiveness to methamphetamine treatment, molecular modeling and comparative immunolocalization that NAT8L is the NAA biosynthetic enzyme Asp-NAT. Aspartic Acid 124-133 N-acetyltransferase 8 like Homo sapiens 239-244 19807691-6 2009 Transfection studies in HEK-293T [human embryonic kidney-293 cells expressing the large T-antigen of SV40 (simian virus 40)] indicated that NAT8L, but not NAT14, catalysed the synthesis of NAA from L-aspartate and acetyl-CoA. Aspartic Acid 198-209 N-acetyltransferase 8 like Homo sapiens 140-145 19807691-7 2009 The specificity of NAT8L, its Km for aspartate and its sensitivity to detergents are similar to those described for brain Asp-NAT. Aspartic Acid 37-46 N-acetyltransferase 8 like Homo sapiens 19-24