PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26567716-6 2015 Initial ASP(+) uptake was inhibited by a cationic uremic metabolites mixture and by the histamine H2-receptor antagonist, cimetidine. Aspartic Acid 8-14 histamine receptor H2 Homo sapiens 88-109 11723228-6 2001 Molecular modeling suggested that the nonconserved Asp-271 in transmembrane domain 7 of gpH2R (Ala-271 in hH2R) confers high potency to guanidines. Aspartic Acid 51-54 histamine receptor H2 Homo sapiens 106-110 11723228-7 2001 This hypothesis was confirmed by Ala-271-->Asp-271 mutation in hH2R-GsalphaS. Aspartic Acid 46-49 histamine receptor H2 Homo sapiens 66-70