PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25360085-9	2014	This might be a general feature in different brain areas since a similar nAChR-mediated bolstering of NMDA-induced ([(3)H]D-Asp) overflow was also observed in hippocampal synaptosomes.	Aspartic Acid	124-127	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	73-78	
24177919-5	2014	In the alpha7 nAChR, it has been found that the ECD contains a ring of ten aspartates (two per subunit) that is believed to face the lumen of the pore and could attract cations for permeation.	Aspartic Acid	75-85	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	14-19	
24177919-6	2014	Using mutagenesis and a combination of electrophysiology and imaging techniques, we tested the possible involvement of these aspartate residues in the calcium permeability of the rat alpha7 nAChR.	Aspartic Acid	125-134	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	190-195	
24177919-7	2014	We found that one of these residues (the aspartate at position 44) appears to be essential since mutating it to alanine resulted in a decrease in amplitude for both whole cell and single-channel responses and in the complete disappearance of detectable calcium changes in most cells, which indicates that the ECD of the alpha7 nAChR plays a key role in calcium permeation.	Aspartic Acid	41-50	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	327-332	
8567173-7	1995	Thus, our results conclude that the Glu-21 residue and the common interaction of the terminal Leu-1 alpha-amino group and the Asp-58 carboxyl group are related to the nAChR-binding activity of cobrotoxin, and the free carboxyl groups in cobrotoxin are conformation-essential.	Aspartic Acid	126-129	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	167-172	
33506493-8	2021	In alpha4beta2 nAChR, the arginine forms a salt-bridge with an aspartate residue in loop B that is necessary for receptor expression, whereas in alpha7 nAChR, this residue is not stabilised by electrostatic interactions, making its side chain highly mobile.	Aspartic Acid	63-72	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	15-20	
33343327-4	2020	Interestingly, this gene cluster contains a non-synonymous single-nucleotide polymorphism (SNP) in the human CHRNA5 gene, causing an aspartic acid (D) to asparagine (N) substitution at amino acid position 398 in the alpha5 nAChR subunit.	Aspartic Acid	133-146	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	223-228	
24950454-1	2014	There occur two rare variations, Asp(D)478Asn(N) and Asp(D)478Glu(E), in the putative cytoplasmic amphipathic alpha-helices of human nicotinic acetylcholine receptor (nAChR) alpha2 subunit as a result of mutation in the 1st (G   A: rs141072985) and 3rd (C   A: rs56344740) nucleotide of its 478th triplet codon (GAC).	Aspartic Acid	33-36	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	133-165	
24950454-1	2014	There occur two rare variations, Asp(D)478Asn(N) and Asp(D)478Glu(E), in the putative cytoplasmic amphipathic alpha-helices of human nicotinic acetylcholine receptor (nAChR) alpha2 subunit as a result of mutation in the 1st (G   A: rs141072985) and 3rd (C   A: rs56344740) nucleotide of its 478th triplet codon (GAC).	Aspartic Acid	33-36	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	167-172