PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32801691-7 2020 In combination therapy with Doxil, only the administration of anti-CTLA-4 before Doxil showed synergism in both non-liposomal and liposomal form and increased the CD8+/regulatory T cell ratio. liposomal doxorubicin 28-33 cytotoxic T-lymphocyte-associated protein 4 Mus musculus 67-73 32042344-9 2020 Furthermore, we found that combining tranilast with Doxil nanomedicine, significantly improved immunostimulatory M1 macrophage content in the tumorigenic tissue and improved the efficacy of the immune checkpoint blocking antibodies anti-PD-1/anti-CTLA-4. liposomal doxorubicin 52-57 cytotoxic T-lymphocyte-associated protein 4 Mus musculus 247-253