PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 148-152 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 165-169 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 165-169 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 148-152 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 165-169 23942212-3 2013 In this study, we compared the therapeutic efficacy of Doxil( ) (commercial doxorubicin-loaded liposomes) and that of Doxil( ) conjugated with anti-CD30 antibodies (CD30-targeted Doxil( )) in treating anaplastic large cell lymphoma (ALCL), a type of T-cell lymphoma characterized by a high CD30 expression. liposomal doxorubicin 118-123 tumor necrosis factor receptor superfamily, member 8 Mus musculus 165-169 23942212-4 2013 Compared to Doxil( ), the CD30-targeted Doxil( ) showed a significantly higher binding affinity to ALCL cells (5.3% versus 27%, p = 0.005) and a lower inhibitory concentration at 50% (IC50) in-vitro (32.6 mug/mL versus 12.6 mug/mL, p = 0.006). liposomal doxorubicin 12-17 tumor necrosis factor receptor superfamily, member 8 Mus musculus 26-30 23942212-4 2013 Compared to Doxil( ), the CD30-targeted Doxil( ) showed a significantly higher binding affinity to ALCL cells (5.3% versus 27%, p = 0.005) and a lower inhibitory concentration at 50% (IC50) in-vitro (32.6 mug/mL versus 12.6 mug/mL, p = 0.006). liposomal doxorubicin 40-45 tumor necrosis factor receptor superfamily, member 8 Mus musculus 26-30 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 47-52 tumor necrosis factor receptor superfamily, member 8 Mus musculus 33-37 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 47-52 tumor necrosis factor receptor superfamily, member 8 Mus musculus 175-179 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 189-194 tumor necrosis factor receptor superfamily, member 8 Mus musculus 33-37 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 189-194 tumor necrosis factor receptor superfamily, member 8 Mus musculus 175-179 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 189-194 tumor necrosis factor receptor superfamily, member 8 Mus musculus 33-37 23942212-5 2013 In a SCID mouse xenograft model, CD30-targeted Doxil( ) inhibited tumor growth more significantly than the unconjugated formulation; specifically, tumors in mice treated with CD30-targeted Doxil( ) were significantly smaller than those in mice treated with Doxil( ) (average, 117 mm(3) versus 270 mm(3), p = 0.001) at 18 days after the tumors were inoculated. liposomal doxorubicin 189-194 tumor necrosis factor receptor superfamily, member 8 Mus musculus 175-179