PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10487690-5 1999 3BetaHSD was present primarily in the microsomal fraction of the human liver, and the rate of DHT reduction to 5alpha-androstane-3beta,17beta-diol (3betaDIOL) by 3betaHSD was 3 times higher than the rate of 3betaHSD oxidation to DHT. Androstane-3,17-diol 148-157 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 0-8 27561382-5 2016 Abiraterone had a significant influence on the metabolism of DHEA, epiandrosterone and 3beta-diol, by the inhibition of the intratumoural 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activities which is one of key catalysts in androgen metabolic pathway. Androstane-3,17-diol 87-97 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 138-172 27561382-5 2016 Abiraterone had a significant influence on the metabolism of DHEA, epiandrosterone and 3beta-diol, by the inhibition of the intratumoural 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activities which is one of key catalysts in androgen metabolic pathway. Androstane-3,17-diol 87-97 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 174-183 27561382-6 2016 The direct-conversion of 3beta-diol to DHT was catalysed by 3beta-HSD and abiraterone could inhibit this activity of 3beta-HSD. Androstane-3,17-diol 25-35 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 60-69 27561382-6 2016 The direct-conversion of 3beta-diol to DHT was catalysed by 3beta-HSD and abiraterone could inhibit this activity of 3beta-HSD. Androstane-3,17-diol 25-35 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 117-126 10487690-5 1999 3BetaHSD was present primarily in the microsomal fraction of the human liver, and the rate of DHT reduction to 5alpha-androstane-3beta,17beta-diol (3betaDIOL) by 3betaHSD was 3 times higher than the rate of 3betaHSD oxidation to DHT. Androstane-3,17-diol 148-157 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 162-170 10487690-5 1999 3BetaHSD was present primarily in the microsomal fraction of the human liver, and the rate of DHT reduction to 5alpha-androstane-3beta,17beta-diol (3betaDIOL) by 3betaHSD was 3 times higher than the rate of 3betaHSD oxidation to DHT. Androstane-3,17-diol 148-157 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 207-215