PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35121040-5 2022 Furthermore, three common pesticides, prochloraz (PCZ), difenoconazole (DFZ) and chlorothalonil (CTL), could significantly inhibit CYP3A-mediated DMM metabolism, and consequently trigger elevated exposure to DMM in vivo. difenoconazole 56-70 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 131-136 35121040-5 2022 Furthermore, three common pesticides, prochloraz (PCZ), difenoconazole (DFZ) and chlorothalonil (CTL), could significantly inhibit CYP3A-mediated DMM metabolism, and consequently trigger elevated exposure to DMM in vivo. difenoconazole 72-75 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 131-136 33575850-11 2021 By contrast, a toxicokinetic interaction was identified including an inhibition of the metabolic enzyme CYP3A4 by fludioxonil and a decreased metabolic conversion of the CYP3A4 substrate difenoconazole when used in mixture experiments. difenoconazole 187-201 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 170-176