PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24346863-5	2014	Additionally, the use of simvastatin plus classII histone deacetylase (HDAC) inhibitor (MC1568) induced further overexpression of p27(KIP1) by inhibiting HDAC5 induction originated from downregulated EZH2 in CRC cells and synergistically led to considerable antiproliferative effects.	MC1568	88-94	histone deacetylase 5	Homo sapiens	154-159	
30321539-11	2018	In accord, boosting nuclear localization of HDAC5 by MC1568 or Go6983 attenuated CaT loss in tachypaced HL-1 cardiomyocytes and preserved contractile function in Drosophila prepupae.	MC1568	53-59	histone deacetylase 5	Homo sapiens	44-49	
31572723-7	2019	We show that siRNAs targeting HDAC5 or HDAC9 can promote neurite growth in SH-SY5Y cells, and that their pharmacological inhibition, using the drug MC1568, promoted neurite growth in cultured rat dopaminergic neurons.	MC1568	148-154	histone deacetylase 5	Homo sapiens	30-35	
31572723-9	2019	In addition, MC1568 or siRNAs targeting HDAC5 or HDAC9 led to an increase in Smad-dependent GFP expression in a reporter assay.	MC1568	13-19	histone deacetylase 5	Homo sapiens	40-45	
31572723-13	2019	Finally, we report that siRNAs targeting HDAC5 or HDAC9 promoted neurite growth in cells overexpressing wild-type or A53T-alpha-synuclein and that MC1568 protected cultured rat dopaminergic neurons against the neurotoxin, MPP+.	MC1568	147-153	histone deacetylase 5	Homo sapiens	41-46	
19498465-5	2009	In skeletal muscle and heart, MC1568 inhibits the activity of HDAC4 and HDAC5 without affecting HDAC3 activity, thereby leaving MEF2-HDAC complexes in a repressed state.	MC1568	30-36	histone deacetylase 5	Homo sapiens	72-77	
33606583-7	2021	Further, pharmacological inhibition of HDAC5 by MC1568 or TMP-195, or knockdown of HDAC5 and the blockade of the nuclear export of HDAC5 by leptomycin B or KPT-330 significantly reduced Ang II-induced Egr-1 expression.	MC1568	48-54	histone deacetylase 5	Homo sapiens	39-44