PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33020270-5	2020	Importantly, combining olaparib with NU7441, a DNA-PKcs inhibitor that blocks NHEJ in HCC, synergistically suppressed HCC growth in both mice and HCC patient-derived-xenograft models.	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	37-43	protein kinase, DNA activated, catalytic polypeptide	Mus musculus	47-55	
27412013-5	2016	In vivo, DNA-PKcs knockdown or oral administration of the DNA-PKcs inhibitor NU-7441 inhibited AKT Ser-473 phosphorylation, HIF-2alpha expression and 786-0 RCC xenograft growth in nude mice.	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	77-84	protein kinase, DNA activated, catalytic polypeptide	Mus musculus	58-66	
32890138-4	2021	METHODS: Fully MHC mismatched murine allogeneic skin graft studies were performed by transplanting skin from BalbC mice to C57bl6 mice and treating with either vehicle or the DNA-PKcs inhibitor NU7441.	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	194-200	protein kinase, DNA activated, catalytic polypeptide	Mus musculus	175-183	
25441643-5	2015	Administration of the DNA-PK inhibitor NU7441 reduced airway eosinophilia, mucus hypersecretion, airway hyperresponsiveness, and OVA-specific IgE production in mice prechallenged with OVA.	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	39-45	protein kinase, DNA activated, catalytic polypeptide	Mus musculus	22-28	
25264192-7	2014	Co-immunoprecipitation (Co-IP) assay results demonstrated that LDI-induced DNA-PKcs-SIN1 complexation, which was inhibited by NU-7441 or SIN1 siRNA-knockdown in mouse osteoblasts.	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	126-133	protein kinase, DNA activated, catalytic polypeptide	Mus musculus	75-83