PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21317303-4	2011	Coffee or caffeic acid (CaA) strongly suppressed mitogen-activated MEK1 and TOPK activities and bound directly to either MEK1 or TOPK in an ATP-noncompetitive manner.	caffeic acid	10-22	PDZ binding kinase	Homo sapiens	76-80	
21317303-4	2011	Coffee or caffeic acid (CaA) strongly suppressed mitogen-activated MEK1 and TOPK activities and bound directly to either MEK1 or TOPK in an ATP-noncompetitive manner.	caffeic acid	10-22	PDZ binding kinase	Homo sapiens	129-133	
21317303-4	2011	Coffee or caffeic acid (CaA) strongly suppressed mitogen-activated MEK1 and TOPK activities and bound directly to either MEK1 or TOPK in an ATP-noncompetitive manner.	caffeic acid	24-27	PDZ binding kinase	Homo sapiens	76-80	
21317303-4	2011	Coffee or caffeic acid (CaA) strongly suppressed mitogen-activated MEK1 and TOPK activities and bound directly to either MEK1 or TOPK in an ATP-noncompetitive manner.	caffeic acid	24-27	PDZ binding kinase	Homo sapiens	129-133	
21317303-7	2011	These results suggest that coffee and CaA target MEK1 and TOPK to suppress colon cancer metastasis and neoplastic cell transformation.	caffeic acid	38-41	PDZ binding kinase	Homo sapiens	58-62