PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28718636-4 2017 The tetradecyl (1c) and hexadecyl (1d) esters of p-coumaric acid and tetradecyl ester of caffeic acid (4c), but not the parental HCAs, were selectively effective against MOLT-4 (human lymphoblastic leukemia) cells with IC50 values of 0.123 +- 0.012, 0.301 +- 0.069 and 1.0 +- 0.1 muM, respectively. caffeic acid 89-101 latexin Homo sapiens 280-283 23030620-6 2012 Furthermore, the inhibition investigation demonstrated that, in the presence of 160 muM S-adenosyl-L-methionine as methyl donor, 5-aza-2"-deoxycytidine, procaine, epicatechin, and caffeic acid could inhibit the M. SssI MTase activity with the IC(50) values of 45.77, 410.3, 129.03, and 124.2 muM, respectively. caffeic acid 180-192 latexin Homo sapiens 84-87 25196644-5 2014 Both caffeic acid and quercetin were potent competitive inhibitors of CYP1A2 (Ki = 1.16 and 0.93 muM, respectively) and CYP2C9 (Ki = 0.95 and 1.67 muM, respectively). caffeic acid 5-17 latexin Homo sapiens 97-100 25196644-5 2014 Both caffeic acid and quercetin were potent competitive inhibitors of CYP1A2 (Ki = 1.16 and 0.93 muM, respectively) and CYP2C9 (Ki = 0.95 and 1.67 muM, respectively). caffeic acid 5-17 latexin Homo sapiens 147-150 25196644-6 2014 Caffeic acid was a potent competitive inhibitor of CYP2D6 (Ki = 1.10 muM) and a weak inhibitor of CYP2C19 and CYP3A4 (IC50 > 100 muM). caffeic acid 0-12 latexin Homo sapiens 69-72 25196644-6 2014 Caffeic acid was a potent competitive inhibitor of CYP2D6 (Ki = 1.10 muM) and a weak inhibitor of CYP2C19 and CYP3A4 (IC50 > 100 muM). caffeic acid 0-12 latexin Homo sapiens 133-136 23685796-10 2013 At 200-800 muM, caffeic acid inhibited cell viability, which was not changed by chelating cytosolic Ca(2+) with 1,2-bis(2-aminophenoxy)ethane-N,N,N",N"-tetraacetic acid-acetoxymethyl ester (BAPTA/AM). caffeic acid 16-28 latexin Homo sapiens 11-14 25153015-3 2014 METHODS: A549 human lung carcinoma cells were treated with 0-100 muM of caffeate derivatives for 0-48 hours. caffeic acid 72-80 latexin Homo sapiens 65-68 23685796-11 2013 Caffeic acid between 400 and 800 muM also induced apoptosis. caffeic acid 0-12 latexin Homo sapiens 33-36 23618190-5 2013 The constructed analytical tool showed a good linearity in the range 0.2-2 muM for caffeic acid and a limit of detection of 0.09 muM. caffeic acid 83-95 latexin Homo sapiens 75-78