PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22227267-2	2012	We explored whether chlorogenic acid and its metabolite, caffeic acid, act directly on skeletal muscle to stimulate 5"-adenosine monophosphate-activated protein kinase (AMPK).	caffeic acid	57-69	protein kinase AMP-activated catalytic subunit alpha 1	Rattus norvegicus	169-173	
22227267-3	2012	Incubation of rat epitrochlearis muscles with Krebs buffer containing caffeic acid (>=0.1 mM, >=30 min) but not chlorogenic acid increased the phosphorylation of AMPKalpha Thr(172), an essential step for kinase activation, and acetyl CoA carboxylase Ser(79), a downstream target of AMPK, in a dose- and time-dependent manner.	caffeic acid	70-82	protein kinase AMP-activated catalytic subunit alpha 1	Rattus norvegicus	168-172	
22227267-6	2012	These results suggest that caffeic acid but not chlorogenic acid acutely stimulates skeletal muscle AMPK activity and insulin-independent glucose transport with a reduction of the intracellular energy status.	caffeic acid	27-39	protein kinase AMP-activated catalytic subunit alpha 1	Rattus norvegicus	100-104