PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33312948-10	2020	Gene expression of PTCH1, SMO, and GLI1 decreased in response to 24 h of treatment with vismodegib or itraconazole.	HhAntag691	88-98	patched 1	Homo sapiens	19-24	
28195165-10	2017	Mechanistically, GDC-0449 treatment markedly decreases the expression levels of key Hedgehog pathway component genes (Shh, Patched-1, Patched-2, smoothened, Gli1 and Gli2).	HhAntag691	17-25	patched 1	Homo sapiens	123-132	
26101701-8	2015	Both Smo and Ptc-1 expression was cooperatively suppressed by SAHA and GDC-0449.	HhAntag691	71-79	patched 1	Homo sapiens	13-18	
33312948-4	2020	This study aimed to investigate the effects of vismodegib and itraconazole on the expression of Hedgehog (HH) genes (PTCH1, SMO, and GLI1), cell cycle and cell death in OSCC cells.	HhAntag691	47-57	patched 1	Homo sapiens	117-122	
29456503-7	2017	Treatment with GDC-0449 markedly reduced expression of Hh target genes GLI1, PTCH1, HIP1, MUC5AC, thus indicating that this pathway is constitutively active in CC cell lines.	HhAntag691	15-23	patched 1	Homo sapiens	77-82