PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34917808-3	2021	In this study, we standardized a rat model of chronic unpredictable stress (CUS) demonstrating cardiovascular dysfunctions and further assessed the effect of IL-6 modulator, diacerein, on cardiovascular functions in CUS exposed rats.	diacerein	174-183	interleukin 6	Rattus norvegicus	158-162	
28025102-0	2017	Somatostatin receptor targeted liposomes with Diacerein inhibit IL-6 for breast cancer therapy.	diacerein	46-55	interleukin 6	Rattus norvegicus	64-68	
31401744-0	2020	Diacerein Downregulates NLRP3/Caspase-1/IL-1beta and IL-6/STAT3 Pathways of Inflammation and Apoptosis in a Rat Model of Cadmium Testicular Toxicity.	diacerein	0-9	interleukin 6	Rattus norvegicus	53-57	
31401744-8	2020	It was concluded that DCN significantly protected the gonads of male rats exposed to cadmium toxicity through modulation of NLRP3/caspase-1/IL-1beta and IL-6/STAT3 pathways of inflammation and apoptosis.	diacerein	22-25	interleukin 6	Rattus norvegicus	153-157	
34917808-6	2021	Moreover, diacerein was administered (50 mg/kg/day x 20 days P.O) post CUS exposure to rats and the serum IL-6 levels and heart functions of CUS rats were determined by ELISA and ECG-HRV analysis, respectively.	diacerein	10-19	interleukin 6	Rattus norvegicus	106-110	
34450401-7	2021	Mechanistically, DIA treatment associated prostatic anti-hyperplastic effects were linked to downregulation of Nrf-2/HO-1 axis, downregulation of inflammatory TNF-a, IL-1beta, IL-6, downregulation of the cell proliferative marker PCNA and upregulation of caspase-3 levels.	diacerein	17-20	interleukin 6	Rattus norvegicus	176-180	
35366176-10	2022	Moreover, DIA dose-dependently alleviated oxidative stress status caused by APAP administration along with inflammatory markers, including the level of interleukin-1 beta (IL-1beta), myeloperoxidase (MPO), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6).	diacerein	10-13	interleukin 6	Rattus norvegicus	251-264	
35366176-10	2022	Moreover, DIA dose-dependently alleviated oxidative stress status caused by APAP administration along with inflammatory markers, including the level of interleukin-1 beta (IL-1beta), myeloperoxidase (MPO), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6).	diacerein	10-13	interleukin 6	Rattus norvegicus	266-270