PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32011533-1 2020 OBJECTIVE: The aim of this study was to investigate the effects of eupatilin on protein kinase D1 (PKD1) and nuclear factor kappa B (NF-kappaB) signaling pathways in cerulein-induced in vitro pancreatitis. eupatilin 67-76 protein kinase D1 Mus musculus 80-97 32011533-1 2020 OBJECTIVE: The aim of this study was to investigate the effects of eupatilin on protein kinase D1 (PKD1) and nuclear factor kappa B (NF-kappaB) signaling pathways in cerulein-induced in vitro pancreatitis. eupatilin 67-76 protein kinase D1 Mus musculus 99-103 32011533-9 2020 Eupatilin inhibited cerulein-induced activation of PKD1/NF-kappaB and the nuclear translocation of NF-kappaB. eupatilin 0-9 protein kinase D1 Mus musculus 51-55 32011533-10 2020 CONCLUSIONS: Our data demonstrated that eupatilin is a potential therapeutic candidate for the treatment of pancreatitis through its ability to reduce cellular necrosis and inflammatory responses by inhibition of the PKD1/NF-kappaB signaling pathway. eupatilin 40-49 protein kinase D1 Mus musculus 217-221