PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15276030-3 2004 Phosphorylation of PLN occurs on residues: serine-16 (Ser(16)) and threonine-17 (Thr(17)) in vivo. Serine 43-49 phospholamban Mus musculus 19-22 26966065-1 2016 Phospholamban (PLN) regulates cardiac type sarco (endo)plasmic reticulum Ca(2+)-ATPase (SERCA2a) via Ser(16)-phosphorylation. Serine 101-104 phospholamban Mus musculus 15-18 26966065-11 2016 These data suggest that PLN is, at least partially, oligo-ubiquitinated at Lys(3) and degraded through Ser(16)-phosphorylation-mediated poly-ubiquitination during heart failure. Serine 103-106 phospholamban Mus musculus 24-27 23624088-6 2013 Concomitantly, relaxation and time constant of [Ca(2+)]i decay (tau) were faster and the phosphorylated fraction of phospholamban (PLN-Ser(16)/PLN) was greater. Serine 135-138 phospholamban Mus musculus 131-134 24892712-2 2014 Mice lacking Epac1 (Epac1 KO) exhibited decreased cardiac contractility with reduced phospholamban (PLN) phosphorylation at serine-16, the major PKA-mediated phosphorylation site. Serine 124-130 phospholamban Mus musculus 100-103 24892712-4 2014 In contrast, direct activation of EPAC in cardiomyocytes led to increased PLN phosphorylation at serine-16, which was dependent on PLC and PKCepsilon. Serine 97-103 phospholamban Mus musculus 74-77 23658728-10 2013 Aerobic exercise trained increased the phosphorylation of PLN at Ser(16) and Thr(17) residues in both KOT and KOCT groups, but carvedilol treatment reduced lipid peroxidation in KOC and KOCT groups compared with KOS group. Serine 65-68 phospholamban Mus musculus 58-61 22484619-9 2012 Conversely, inhibition of cGMP/PKG pathway abolished the Ang II-induced faster relaxation by reducing phospholamban (PLN) Ser(16) phosphorylation. Serine 122-125 phospholamban Mus musculus 117-120 20942811-5 2011 Western blots were carried out on myocyte extracts with antibodies against total phospholamban (PLN) and PLN phosphorylated at serine-16. Serine 127-133 phospholamban Mus musculus 105-108 20942811-8 2011 Urocortin 2 also increased PLN phosphorylation at serine-16. Serine 50-56 phospholamban Mus musculus 27-30 15276030-3 2004 Phosphorylation of PLN occurs on residues: serine-16 (Ser(16)) and threonine-17 (Thr(17)) in vivo. Serine 54-57 phospholamban Mus musculus 19-22 34138844-10 2021 After ISO withdrawal, phosphorylation of phospholamban (PLN) at the protein kinase A (PKA) phosphorylation site Ser-16 dropped down to 20% as compared to only 50% at the Ca2+/Calmodulin-dependent kinase II (CaMKII) phosphorylation site Thr-17 in "ISO off" mice. Serine 112-115 phospholamban Mus musculus 56-59 10809743-7 2000 The use of antibodies specific against Ser(16)- and Thr(17)-PLN peptides showed that phosphorylation of both pentameric and monomeric PLN were increased between 1.2- and 2.4-fold in both the L37A and I40A lines but not in the wtOE line. Serine 39-42 phospholamban Mus musculus 134-137