PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18031291-2	2008	In class A beta-lactamases, such as TEM-1 and SHV-1, residues adjacent to the active-site serine residue play a crucial role in inhibitor resistance and substrate selectivity.	Serine	90-96	hypothetical protein	Escherichia coli	36-41	
9174192-6	1997	This enzyme differed from TEM-1 (blaT-1B gene) by four amino acid substitutions: Met-->Leu-69, Glu-->Lys-104, Gly-->Ser-238 and Asn-->Asp-276.	Serine	125-128	hypothetical protein	Escherichia coli	26-31	
16262787-6	2005	Site-directed mutagenesis of the catalytic Ser of TEM-1, but not Oxa-3, abolished the biofilm defect, while disruption of either TEM-1 or Oxa-3 expression restored wild-type levels of biofilm formation.	Serine	43-46	hypothetical protein	Escherichia coli	50-55	
14534312-2	2003	In TEM-1 and SHV-1, the common class A beta-lactamases, alterations at Ser-130 confer resistance to inactivation by the beta-lactamase inhibitors, clavulanic acid, and tazobactam.	Serine	71-74	hypothetical protein	Escherichia coli	3-8	
8239618-3	1993	Both TEM-10 sequences differed from TEM-1 by substitutions of Ser-162 and Lys-237.	Serine	62-65	hypothetical protein	Escherichia coli	5-10	
8877532-3	1996	The blaIRT gene differs from blaTEM-2 gene by one point mutation which leads to the amino-acid substitution Arg-->Ser at position 244, as observed for the original IRT-2 enzyme derived from TEM-1 reported in Escherichia coli.	Serine	117-120	hypothetical protein	Escherichia coli	193-198	
8067751-5	1994	The doubly mutated derivative of the TEM-1 enzyme (Ser-164/Ser-244) retains the characteristics of the Ser-164 mutant enzyme, i.e., enhanced activity against ceftazidime and sensitivity to inactivation by clavulanate.	Serine	51-54	hypothetical protein	Escherichia coli	37-42	
35052944-5	2022	Here, by using  ampD and  ampE mutants of E. coli, we attempted to elucidate the effects of ampD and ampE on the expression of serine-BLAs originating from Enterobacteriaceae, viz., CTX-M-15, TEM-1 and OXA-2.	Serine	127-133	hypothetical protein	Escherichia coli	192-197