PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33924467-14	2021	Overall, kurarinone showed an anti-inflammatory effect by inhibiting Th1 and Th17 cell differentiation and an antioxidant effect exerted in part through activating the Nrf-2/KEAP-1 pathway.	kurarinone	9-19	nuclear factor, erythroid derived 2, like 2	Mus musculus	168-173	
32916869-0	2020	Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway.	kurarinone	30-40	nuclear factor, erythroid derived 2, like 2	Mus musculus	82-86	
32916869-4	2020	In the present study, we demonstrated that kurarinone activated Nrf2 and increased the expression of antioxidant enzymes, including heme oxygenase-1 (HO-1).	kurarinone	43-53	nuclear factor, erythroid derived 2, like 2	Mus musculus	64-68	
32916869-5	2020	Mechanistically, kurarinone downregulated the expression of kelch-like ECH-associated protein 1 (KEAP1), subsequently leading to the activation of Nrf2.	kurarinone	17-27	nuclear factor, erythroid derived 2, like 2	Mus musculus	147-151	
32916869-8	2020	These results indicate that kurarinone activates the KEAP1/Nrf2 pathway to induce HO-1 expression, thereby exerting immunosuppressive effects.	kurarinone	28-38	nuclear factor, erythroid derived 2, like 2	Mus musculus	59-63