PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21612861-12	2011	In the in vivo studies, calycosin stimulated a dramatic increase in uterine weight and downregulated the level of ERalpha protein in OVX mice.	7,3'-dihydroxy-4'-methoxyisoflavone	24-33	estrogen receptor 1 (alpha)	Mus musculus	114-121	
33647882-0	2021	Calycosin stimulates the proliferation of endothelial cells, but not breast cancer cells, via a feedback loop involving RP11-65M17.3, BRIP1 and ERalpha.	7,3'-dihydroxy-4'-methoxyisoflavone	0-9	estrogen receptor 1 (alpha)	Mus musculus	144-151	
33647882-3	2021	In the present study, we show that the phytoestrogen calycosin (20 muM) stimulated the proliferation of ECs (HUVECs and HMEC-1) but inhibited the growth of breast cancer cells (BCCs) expressing ERalpha (MCF-7 and T47D).	7,3'-dihydroxy-4'-methoxyisoflavone	53-62	estrogen receptor 1 (alpha)	Mus musculus	194-201	
32474674-11	2021	Importantly, calycosin improved ERbeta protein expression, JAK2 and STAT3 mRNA expressions, p-JAK2/JAK2, and p-STAT3/STAT3 relative protein expressions.	7,3'-dihydroxy-4'-methoxyisoflavone	13-22	estrogen receptor 1 (alpha)	Mus musculus	32-38	
32474674-13	2021	Calycosin significantly inhibits liver fibrosis in mice, and its mechanism may involve the following: calycosin inhibits oxidative stress; calycosin inhibits collagen synthesis and balances MMP-1/TIMP-1 system; calycosin increases ERbeta expression and activates JAK2-STAT3 pathway.	7,3'-dihydroxy-4'-methoxyisoflavone	0-9	estrogen receptor 1 (alpha)	Mus musculus	231-237	
32474674-13	2021	Calycosin significantly inhibits liver fibrosis in mice, and its mechanism may involve the following: calycosin inhibits oxidative stress; calycosin inhibits collagen synthesis and balances MMP-1/TIMP-1 system; calycosin increases ERbeta expression and activates JAK2-STAT3 pathway.	7,3'-dihydroxy-4'-methoxyisoflavone	139-148	estrogen receptor 1 (alpha)	Mus musculus	231-237	
32474674-13	2021	Calycosin significantly inhibits liver fibrosis in mice, and its mechanism may involve the following: calycosin inhibits oxidative stress; calycosin inhibits collagen synthesis and balances MMP-1/TIMP-1 system; calycosin increases ERbeta expression and activates JAK2-STAT3 pathway.	7,3'-dihydroxy-4'-methoxyisoflavone	139-148	estrogen receptor 1 (alpha)	Mus musculus	231-237