PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20870729-9 2010 We propose that CD38 is an NAADP synthase required for coupling receptor activation to NAADP-mediated Ca(2+) release from lysosomal stores in pancreatic acinar cells. NAADP 27-32 CD38 molecule Rattus norvegicus 16-20 25078456-1 2015 CD38 is a multifunctional enzyme that catalyzes the formation of the endogenous Ca(2+)-mobilizing messengers cyclic ADP-ribose (cADPR) and nicotinic acid adenosine dinucleotide phosphate (NAADP) for the activation of ryanodine receptors (RyRs) of sarcoplasmic reticulum and NAADP-sensitive Ca(2+) release channels in endolysosomes, respectively. NAADP 188-193 CD38 molecule Rattus norvegicus 0-4 25078456-1 2015 CD38 is a multifunctional enzyme that catalyzes the formation of the endogenous Ca(2+)-mobilizing messengers cyclic ADP-ribose (cADPR) and nicotinic acid adenosine dinucleotide phosphate (NAADP) for the activation of ryanodine receptors (RyRs) of sarcoplasmic reticulum and NAADP-sensitive Ca(2+) release channels in endolysosomes, respectively. NAADP 274-279 CD38 molecule Rattus norvegicus 0-4 11829748-2 2002 In rat tissues, we observed that the capacity for NAADP synthesis could be co-immunoprecipitated with CD38 using an anti-CD38 antibody. NAADP 50-55 CD38 molecule Rattus norvegicus 102-106 11829748-2 2002 In rat tissues, we observed that the capacity for NAADP synthesis could be co-immunoprecipitated with CD38 using an anti-CD38 antibody. NAADP 50-55 CD38 molecule Rattus norvegicus 121-125 18288637-4 2008 In addition, we show that lipid rafts/caveolae contain ETA, ETB, and NAADP/cADPR generating enzyme CD38 and that stimulation of ETB receptors results in increased CD38 activity; interestingly, ETB- (but not ETA-) mediated Ca(2+) responses were antagonized by disruption of lipid rafts/caveolae with methyl-beta-cyclodextrin. NAADP 69-74 CD38 molecule Rattus norvegicus 99-103