PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16969344-6 2006 Overexpressing Bcl-2 inhibited cerulenin-mediated cell death. Cerulenin 31-40 BCL2 apoptosis regulator Homo sapiens 15-20 16546963-8 2006 Treatment of cells with cerulenin and LY294002 down-regulated the protein levels of X chromosome-linked inhibitor of apoptosis (XIAP), cellular inhibitor of apoptosis 1 (cIAP-1), and Akt, whereas the levels of mitogen-activated protein/extracellular signal-regulated kinase kinase and other antiapoptotic Bcl-2 family proteins (Bcl-2 and Bcl-xl) did not change. Cerulenin 24-33 BCL2 apoptosis regulator Homo sapiens 305-310 16546963-8 2006 Treatment of cells with cerulenin and LY294002 down-regulated the protein levels of X chromosome-linked inhibitor of apoptosis (XIAP), cellular inhibitor of apoptosis 1 (cIAP-1), and Akt, whereas the levels of mitogen-activated protein/extracellular signal-regulated kinase kinase and other antiapoptotic Bcl-2 family proteins (Bcl-2 and Bcl-xl) did not change. Cerulenin 24-33 BCL2 apoptosis regulator Homo sapiens 328-333 11866947-8 2000 bcl-2 oncoprotein expression rate was significantly lower in cerulenin-treated group in comparing with the control group. Cerulenin 61-70 BCL2 apoptosis regulator Homo sapiens 0-5 11866947-11 2000 The mechanism of cell death may be correlated with apoptosis, and bcl-2 and bax gene may play an important role in regulating cerulenin-induced apoptosis. Cerulenin 126-135 BCL2 apoptosis regulator Homo sapiens 66-71