PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9781939-1 1998 The antihypertensive efficacy of a 1.5-mg sustained-release formulation (SR 1.5) of indapamide, a diuretic related to thiazide, has been pointed out by using conventional sphygmomanometric measurement 24 h after dosing in clinic, in two large European randomized, double-blind, controlled studies (2 and 3 months). Indapamide 84-94 ADP ribosylation factor like GTPase 6 interacting protein 4 Homo sapiens 73-79 9781939-6 1998 The trough-to-peak ratio--not previously calculated for a diuretic according to international guidelines--meets Food and Drug Administration requirements and confirms the 24-h efficacy of indapamide SR 1.5. Indapamide 188-198 ADP ribosylation factor like GTPase 6 interacting protein 4 Homo sapiens 199-205