PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11026649-9 2000 Furthermore, high-dose indapamide increased plasma renin activity substantially, whereas low-dose treatment was without effect on circulating renin. Indapamide 23-33 renin Rattus norvegicus 51-56 11026649-10 2000 In conclusion, in rats with continuous LV pressure-overload low-dose treatment with indapamide leads to mild regression of cardiac hypertrophy, accompanied by a downregulation of components of the cardiac renin-angiotensin system. Indapamide 84-94 renin Rattus norvegicus 205-210