PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29405807-0	2019	Interaction of deoxyschizandrin and schizandrin B with liver uptake transporters OATP1B1 and OATP1B3.	schizandrin A	15-31	solute carrier organic anion transporter family member 1B1	Homo sapiens	81-88	
29405807-5	2019	Deoxyschizandrin exhibited a high affinity for OATP1B1 with Km of 17.61 +- 0.43 muM but a low affinity for OATP1B3.	schizandrin A	0-16	solute carrier organic anion transporter family member 1B1	Homo sapiens	47-54	
29405807-8	2019	Atorvastatin and rifampicin could inhibit the uptake of deoxyschizandrin and schizandrin B mediated by OATP1B1.	schizandrin A	56-72	solute carrier organic anion transporter family member 1B1	Homo sapiens	103-110	
29405807-10	2019	Intriguingly, both deoxyschizandrin and schizandrin B significantly promoted the uptake of atorvastatin (with EC50 of 50.58 +- 8.08 and 24.70 +- 5.82 microM, respectively) and rosuvastatin (with EC50 of 13.46 +- 2.70 and 8.99 +- 4.73 microM, respectively) mediated by OATP1B1.	schizandrin A	19-35	solute carrier organic anion transporter family member 1B1	Homo sapiens	268-275	
29405807-11	2019	Deoxyschizandrin could markedly promote the uptake of fluvastatin but inhibit the uptake of sodium taurocholate (TCNa) mediated by OATP1B1.	schizandrin A	0-16	solute carrier organic anion transporter family member 1B1	Homo sapiens	131-138	
29405807-13	2019	The promotion on hepatic uptake of statins mediated by OATP1B1 might lead to enhanced efficacy of cholesterol lowering and reduced risk of myopathy for hyperlipidemia patients when given statins together with deoxyschizandrin or schizandrin B.	schizandrin A	209-225	solute carrier organic anion transporter family member 1B1	Homo sapiens	55-62	
25975095-4	2015	In this study, we aimed to investigate the effect of schisandrin A, schisandrin B and tanshinone IIA, which were extracted from medicinal plants, on OATP1B1 activity.	schizandrin A	53-66	solute carrier organic anion transporter family member 1B1	Homo sapiens	149-156	
25975095-7	2015	We found that schisandrin A and B increased OATP1B1 mRNA levels by 1.81-fold (p < 0.01) and 1.87-fold (p < 0.01) at concentration of 10 muM, respectively.	schizandrin A	14-27	solute carrier organic anion transporter family member 1B1	Homo sapiens	44-51