PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30063113-8 2018 In this study we evaluated the complexation of insulin glulisine, an insulin analogue administered subcutaneously or intravenously in clinical practice, with a well-known CPP modified with the MCFA lauric acid. lauric acid 198-209 insulin Homo sapiens 47-54 35466692-11 2022 CB metabolites, such as lauric acid, a medium chain FA which may improve insulin sensitivity, were associated with neonatal adiposity differently between offspring of women with and without obesity. lauric acid 24-35 insulin Homo sapiens 73-80 1593871-7 1992 Thus, while adipic acid (C6) had no effect, Caprylic acid (C8) had a minimal effect that was not statistically significant, but capric acid (C10) and lauric acid had very potent effects that were of the same magnitude to the effect of linoleate on insulin secretion. lauric acid 150-161 insulin Homo sapiens 248-255 1593871-8 1992 When insulin output was assessed as the mean integrated area under the curve during a 20-min perifusion, 5 mM lauric acid enhanced insulin secretion from a basal 7351 +/- 666 pg to 15,756 +/- 1680 pg (P less than 0.01, n = 5). lauric acid 110-121 insulin Homo sapiens 5-12 35499234-0 2022 Lauric acid impairs insulin-induced Akt phosphorylation by upregulating SELENOP expression via HNF4alpha induction. lauric acid 0-11 insulin Homo sapiens 20-27 35499234-10 2022 Thus, the lauric acid-induced impairment of Akt phosphorylation brought about by insulin was rescued by the knockdown of either Hnf4alpha or Selenop. lauric acid 10-21 insulin Homo sapiens 81-88 3758926-8 1986 While in the MC-treated patients there was some positive correlation between the insulin dose and the level of Abl no significant correlation was found between the diabetes control and insulin antibody titers in both groups of patients. lauric acid 111-114 insulin Homo sapiens 81-88 33259010-0 2020 Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages. lauric acid 0-11 insulin Homo sapiens 23-30 33259010-4 2020 This research objective was to uncover the effects of the lauric acid on glucose uptake, mitochondrial function and mitochondrial biogenesis in insulin-resistant macrophages. lauric acid 58-69 insulin Homo sapiens 144-151 33259010-6 2020 Glucose uptake assay, cellular ROS and ATP production assays, mitochondrial content and membrane potential assay were carried out to analyse the effects of lauric acid on insulin resistance and mitochondrial biogenesis in the macrophages. lauric acid 156-167 insulin Homo sapiens 171-178 33259010-11 2020 We show here that lauric acid has the potential to improve insulin sensitivity and mitochondrial dysregulation in insulin-resistant macrophages. lauric acid 18-29 insulin Homo sapiens 59-66 33259010-11 2020 We show here that lauric acid has the potential to improve insulin sensitivity and mitochondrial dysregulation in insulin-resistant macrophages. lauric acid 18-29 insulin Homo sapiens 114-121