PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10648600-0 2000 Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder. lauric acid 92-95 interferon regulatory factor 8 Mus musculus 14-59 10648600-0 2000 Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder. lauric acid 92-95 interferon regulatory factor 8 Mus musculus 61-66 10648600-7 2000 We found that expression of the ICSBP protein was significantly decreased in Bcr-Abl-induced CML-like disease. lauric acid 81-84 interferon regulatory factor 8 Mus musculus 32-37 10648600-8 2000 Forced coexpression of ICSBP inhibited the Bcr-Abl-induced colony formation of BM cells from 5-FU-treated mice in vitro and Bcr-Abl-induced CML-like disease in vivo. lauric acid 47-50 interferon regulatory factor 8 Mus musculus 23-28 10648600-8 2000 Forced coexpression of ICSBP inhibited the Bcr-Abl-induced colony formation of BM cells from 5-FU-treated mice in vitro and Bcr-Abl-induced CML-like disease in vivo. lauric acid 128-131 interferon regulatory factor 8 Mus musculus 23-28 10648600-10 2000 Overexpression of ICSBP consistently promotes rather than inhibits Bcr-Abl-induced B lymphoproliferation in a murine model where BM cells from non-5-FU-treated donors were used, indicating that ICSBP has a specific antitumor activity toward myeloid neoplasms. lauric acid 71-74 interferon regulatory factor 8 Mus musculus 18-23 24101380-5 2013 Combined Irf8 deletion and constitutive beta-catenin activation result in progression of CML into fatal blast crisis, elevated leukemic potential of BCR-ABL-induced LICs, and Imatinib resistance. lauric acid 153-156 interferon regulatory factor 8 Mus musculus 9-13