PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25324206-5 2015 Benomyl and prochloraz, but not vinclozolin or atrazine, decreased levels of CYP17 gene and protein expression, as well as catalytic activity in H295R cells. prochloraz 12-22 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 77-82 22198065-5 2012 Exposure to prochloraz resulted in increased hormone levels upstream of steroid 17 alpha-hydroxylase/17,20 lyase (P450c17) and decreases downstream. prochloraz 12-22 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 72-112 22198065-5 2012 Exposure to prochloraz resulted in increased hormone levels upstream of steroid 17 alpha-hydroxylase/17,20 lyase (P450c17) and decreases downstream. prochloraz 12-22 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 114-121 19733639-4 2009 Analysis of the dose-dependent effects of prochloraz on the secretion of steroidogenic intermediates suggested that the observed effects on cortisol and aldosterone secretion might be mediated by inhibition of the steroidogenic steps catalysed by CYP17A1 and CYP21A2. prochloraz 42-52 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 247-254 19733639-6 2009 In addition, analysis of enzyme activity showed a dose-dependent inhibitory effect of prochloraz on the activity of CYP17A1 and CYP21A2, but not CYP11B1. prochloraz 86-96 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 116-123