PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35101006-12	2022	The expression of Bcl-2 mRNA was down-regulated by the high(3000 mug/ml) dose group of ethyl acetate extract.	ethyl acetate	87-100	BCL2 apoptosis regulator	Homo sapiens	18-23	
32512042-9	2020	And the HepG2 cells induced at the ethyl acetate fraction could up-regulate Bax gene and protein, while down-regulating Bcl-2 gene and protein (P < 0.05) during S phase in a dose-dependent manner.	ethyl acetate	35-48	BCL2 apoptosis regulator	Homo sapiens	120-125	
33040785-9	2020	Results showed that ethyl acetate extract of peony seed coat could reduce cell proliferation rate and the protein levels of PCNA, Bcl-2, p-STAT3, Survivin and the expression level of miR-424-3p (P<0.05), increase apoptosis rate and the protein level of Bax (P<0.05).	ethyl acetate	20-33	BCL2 apoptosis regulator	Homo sapiens	130-135	
25356658-0	2015	Ethyl acetate extract from Glycosmis parva leaf induces apoptosis and cell-cycle arrest by decreasing expression of COX-2 and altering BCL-2 family gene expression in human colorectal cancer HT-29 cells.	ethyl acetate	0-13	BCL2 apoptosis regulator	Homo sapiens	135-140	
17203183-0	2007	Ethyl acetate extract of Chinese medicinal herb Sarcandra glabra induces growth inhibition on human leukemic HL-60 cells, associated with cell cycle arrest and up-regulation of pro-apoptotic Bax/Bcl-2 ratio.	ethyl acetate	0-13	BCL2 apoptosis regulator	Homo sapiens	195-200	
23435602-6	2013	An ethyl acetate (EtOAc) extract exhibited the highest cytotoxicity and resulted in an up-regulated expression of the pro-apoptotic protein Bax (bcl-2 associated X protein) and a down-regulated expression of the anti-apoptotic protein Bcl2 in both SW480 and MCF7 cells.	ethyl acetate	3-16	BCL2 apoptosis regulator	Homo sapiens	235-239	
23435602-6	2013	An ethyl acetate (EtOAc) extract exhibited the highest cytotoxicity and resulted in an up-regulated expression of the pro-apoptotic protein Bax (bcl-2 associated X protein) and a down-regulated expression of the anti-apoptotic protein Bcl2 in both SW480 and MCF7 cells.	ethyl acetate	18-23	BCL2 apoptosis regulator	Homo sapiens	235-239	
16361073-0	2006	Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/Bcl-X(L) expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation.	ethyl acetate	0-13	BCL2 apoptosis regulator	Homo sapiens	78-83