PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15494417-4 2005 At a concentration of 1 microM, ouabain and other tested cardenolides, as well as bufadienolides such as bufalin, cinobufagin, cinobufotalin, and telobufotoxin, led to approximately 10-fold inhibition of the Na(+),K(+) pump, a 2-3-fold decrease in staining with dimethylthiazol-diphenyltetrazolium (MTT), and massive death indicated by detachment of approximately 80% of cells and caspase-3 activation. cinobufotalin 127-140 caspase 3 Canis lupus familiaris 381-390