PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27713569-5 2016 A single dose of TCDD administered to adult mice induced Ahr-dependent CpG hypomethylation, changes in histone modifications, and thymine DNA glycosylase (Tdg) recruitment at the Cyp1a1 promoter in the liver within 24 hrs. Polychlorinated Dibenzodioxins 17-21 thymine DNA glycosylase Mus musculus 130-153 27713569-5 2016 A single dose of TCDD administered to adult mice induced Ahr-dependent CpG hypomethylation, changes in histone modifications, and thymine DNA glycosylase (Tdg) recruitment at the Cyp1a1 promoter in the liver within 24 hrs. Polychlorinated Dibenzodioxins 17-21 thymine DNA glycosylase Mus musculus 155-158 27713569-7 2016 Our demethylation assay using siRNA knockdown and an in vitro methylated plasmid showed that Ahr, Tdg, and the ten-eleven translocation methyldioxygenases Tet2 and Tet3 are required for the TCDD-induced DNA demethylation. Polychlorinated Dibenzodioxins 190-194 thymine DNA glycosylase Mus musculus 98-101