PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22539624-6 2012 TCDD also induced oleate levels threefold in Scd1 null mice that are incapable of desaturating stearate (18:0). Polychlorinated Dibenzodioxins 0-4 stearoyl-Coenzyme A desaturase 1 Mus musculus 45-49 28973660-5 2017 When applying TCDD and beta-naphthoflavone, another AhR agonist, on the ears of C57BL/6J mice, we reproduced (1) an atrophy of sebaceous glands, (2) a strong induction of CYP1A1 within the glands, and (3) a dramatic repression of the genes encoding the sebogenic enzymes AWAT1, ELOVL3, and SCD1. Polychlorinated Dibenzodioxins 14-18 stearoyl-Coenzyme A desaturase 1 Mus musculus 290-294 22539624-8 2012 Moreover, TCDD increased hepatic (14)C-oleate levels twofold in wild type and 2.4-fold in Scd1 null mice concurrent with the induction of intestinal and hepatic lipid transport genes (Slc27a, Fabp, Ldlr, Cd36, and Apob). Polychlorinated Dibenzodioxins 10-14 stearoyl-Coenzyme A desaturase 1 Mus musculus 90-94 21890736-0 2011 Aryl hydrocarbon receptor-mediated induction of Stearoyl-CoA desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis. Polychlorinated Dibenzodioxins 115-119 stearoyl-Coenzyme A desaturase 1 Mus musculus 48-73 21890736-4 2011 TCDD induced Scd1 activity, protein, and messenger RNA (mRNA) levels approximately twofold. Polychlorinated Dibenzodioxins 0-4 stearoyl-Coenzyme A desaturase 1 Mus musculus 13-17 21890736-10 2011 In Scd1(-/-) mice, TCDD induced minimal hepatic vacuolization and inflammation, while serum ALT levels remained unchanged. Polychlorinated Dibenzodioxins 19-23 stearoyl-Coenzyme A desaturase 1 Mus musculus 3-7 21890736-12 2011 In Scd1(-/-) mice, TCDD induced SFA ratios 8%, reduced MUFA ratios 13%, and induced polyunsaturated fatty acid ratios 5% relative to treated Scd1(+/+) mice. Polychlorinated Dibenzodioxins 19-23 stearoyl-Coenzyme A desaturase 1 Mus musculus 3-7 21890736-12 2011 In Scd1(-/-) mice, TCDD induced SFA ratios 8%, reduced MUFA ratios 13%, and induced polyunsaturated fatty acid ratios 5% relative to treated Scd1(+/+) mice. Polychlorinated Dibenzodioxins 19-23 stearoyl-Coenzyme A desaturase 1 Mus musculus 141-145 14505802-2 2003 TCDD clearly suppressed differentiation of MEF+/+, but not MEF-/-, as measured by increased accumulation of triglycerides associated with increased expression of adipocyte differentiation-specific genes such as peroxisome proliferators activated receptor (PPAR)gamma, stearoyl-CoA desaturase (SCD-1). Polychlorinated Dibenzodioxins 0-4 stearoyl-Coenzyme A desaturase 1 Mus musculus 293-298