PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8937476-5 1996 Consistent with these results, TCDD-induced c-Src kinase activity was abolished when c-Src immunoprecipitate"s suspension was preincubated with 0.1 or 1 microM alpha-naphthoflavone (AhR blocker) for 10 min prior to the addition of TCDD. Polychlorinated Dibenzodioxins 31-35 c-src tyrosine kinase Mus musculus 44-56 9664232-0 1998 Use of c-Src and c-Fos knockout mice for the studies on the role of c-Src kinase signaling in the expression of toxicity of TCDD. Polychlorinated Dibenzodioxins 124-128 c-src tyrosine kinase Mus musculus 68-80 9664232-3 1998 First, we could show that chemical inhibition of c-src kinase could produce practically the same phenomenon of reduced toxicity of TCDD in wild-type mice cotreated with geldanamycin, a specific chemical inhibitor known to suppress c-src kinase. Polychlorinated Dibenzodioxins 131-135 c-src tyrosine kinase Mus musculus 49-61 9628558-6 1998 The gender-specific mechanisms of TCDD-induced toxicity appear to involve c-Src kinase, nPKC epsilon, and pan-Ras, as well as overlap in the cytosolic signal transduction pathways of TCDD and sex steroids. Polychlorinated Dibenzodioxins 34-38 c-src tyrosine kinase Mus musculus 74-86 8937476-5 1996 Consistent with these results, TCDD-induced c-Src kinase activity was abolished when c-Src immunoprecipitate"s suspension was preincubated with 0.1 or 1 microM alpha-naphthoflavone (AhR blocker) for 10 min prior to the addition of TCDD. Polychlorinated Dibenzodioxins 231-235 c-src tyrosine kinase Mus musculus 44-56 8937476-6 1996 In addition, pretreatment of 3T3 fibroblast cells with 3-methylcholanthrene abolished TCDD-induced c-Src kinase activity in AhR-immunoprecipitate. Polychlorinated Dibenzodioxins 86-90 c-src tyrosine kinase Mus musculus 99-111