PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24587053-6	2014	In addition, TCDD exposure altered the expression of senescence marker proteins, such as p16, p21 and p-Rb, in both dose- and time-dependent manners.	Polychlorinated Dibenzodioxins	13-17	RB transcriptional corepressor 1	Homo sapiens	102-106	
16009159-12	2005	The ability of TCDD to selectively down-regulate stromal PR-B expression and increase MMP expression in both stromal and epithelial cells suggests that exposure to this toxin may negatively impact P-mediated cell-cell communication in the human endometrium.	Polychlorinated Dibenzodioxins	15-19	RB transcriptional corepressor 1	Homo sapiens	57-61	
15322241-0	2004	2,3,7,8-Tetrachlorodibenzo-p-dioxin blocks androgen-dependent cell proliferation of LNCaP cells through modulation of pRB phosphorylation.	Polychlorinated Dibenzodioxins	0-35	RB transcriptional corepressor 1	Homo sapiens	118-121	
19917880-9	2010	In vitro assays for CDK4 kinase activity demonstrated that RB1 phosphorylation by the AHR/CDK4/CCND1 complex was reduced in the presence of TCDD.	Polychlorinated Dibenzodioxins	140-144	RB transcriptional corepressor 1	Homo sapiens	59-62	
15157999-6	2004	However, TCDD induced an enhanced expression of p27 and a hypophosphorylation of pRb, which was prevented by alpha-NF and MOP.	Polychlorinated Dibenzodioxins	9-13	RB transcriptional corepressor 1	Homo sapiens	81-84	
15157999-7	2004	Combined, these results suggest that the TCDD-induced inhibition of neuronal cell proliferation may be due to the AhR-dependent G(1) arrest through an enhanced expression of p27 and a hypophosphorylation of pRB.	Polychlorinated Dibenzodioxins	41-45	RB transcriptional corepressor 1	Homo sapiens	207-210	
9712901-5	1998	We examined whether the human AhR or its dimerization partner, the AhR nuclear translocator, interacts with pRb as a basis of the TCDD-induced cell cycle arrest.	Polychlorinated Dibenzodioxins	130-134	RB transcriptional corepressor 1	Homo sapiens	108-111	
9535862-9	1998	For the repressive effects of hPR-B, however, additional gene expression seems to be involved, as only the agonist-bound, wild-type hPR-B could clearly repress the TCDD-induced response.	Polychlorinated Dibenzodioxins	164-168	RB transcriptional corepressor 1	Homo sapiens	132-137