PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9630460-4	1998	Interestingly, in thymocytes from mice treated with a single dose of 50 micrograms/kg body wt of TCDD, there was a significant increase in the density of expression of CD3, alpha beta TCR, CD44, and IL-2R, and a decrease in the expression of J11d, CD4, and CD8 molecules when compared to the control thymocytes.	Polychlorinated Dibenzodioxins	97-101	interleukin 2 receptor, alpha chain	Mus musculus	199-204	
14718643-9	2004	Furthermore, apoptosis-associated phenotypic changes were found in thymocytes of mice perinatally exposed to TCDD, characterized by an increase in expression of CD3, alphabetaTCR, IL-2R, and CD44, and a decrease in CD4, CD8, and J11d markers.	Polychlorinated Dibenzodioxins	109-113	interleukin 2 receptor, alpha chain	Mus musculus	180-185	
17337447-7	2007	Administration of a 100 microg/kg dose of TCDD results in a approximately 15-fold induction of KLF2 as early as the TN2 (CD44(+), CD25(+)) stage of development and immediately precedes acute cell loss in the TN3, TN4, and double positive (CD4(+), CD8(+)) cell stages.	Polychlorinated Dibenzodioxins	42-46	interleukin 2 receptor, alpha chain	Mus musculus	130-134	
2303704-7	1990	Intrathymic CD4/CD8 and IL-2R expression demonstrated only mild alterations after exposure to 30 micrograms TCDD/kg.	Polychlorinated Dibenzodioxins	108-112	interleukin 2 receptor, alpha chain	Mus musculus	24-29	
20007828-10	2010	Development of EAU was completely suppressed by TCDD injection, and suppression was abolished by treatment with anti-CD25 mAb before TCDD injection.	Polychlorinated Dibenzodioxins	133-137	interleukin 2 receptor, alpha chain	Mus musculus	117-121	
20007828-14	2010	Activation of AHR by TCDD markedly suppressed autoimmune uveoretinitis through mechanisms that expand CD25(+)Foxp3(+) T(reg) cells and interfere with the activation of Th1 and Th17 cells.	Polychlorinated Dibenzodioxins	21-25	interleukin 2 receptor, alpha chain	Mus musculus	102-106	
18684927-0	2008	Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.	Polychlorinated Dibenzodioxins	121-156	interleukin 2 receptor, alpha chain	Mus musculus	65-69	
18684927-2	2008	Mice exposed to TCDD during an acute B6-into-B6D2F1 graft-vs-host response do not develop disease, and recently this has been shown to correlate with the generation of CD4(+) T cells that express CD25 and demonstrate in vitro suppressive function.	Polychlorinated Dibenzodioxins	16-20	interleukin 2 receptor, alpha chain	Mus musculus	196-200	
20350561-6	2010	TCDD decreased CD11c expression but increased MHC class II, CD86 and CD25 expression on the BMDCs.	Polychlorinated Dibenzodioxins	0-4	interleukin 2 receptor, alpha chain	Mus musculus	69-73