PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33900313-0	2021	Apoptotic mechanisms of gastric cancer cells induced by isolated erinacine S through epigenetic histone H3 methylation of FasL and TRAIL.	erinacine S	65-74	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	131-136	
33900313-5	2021	Furthermore, immunohistochemical analyses revealed that erinacine S treatment significantly increases the FasL and TRAIL protein, whereas it decreases the levels of PCNA and cyclin D1 in the gastric cancer xenograft mice.	erinacine S	56-65	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	115-120	
33900313-6	2021	Consistently, in AGS cells, erinacine S treatment not only triggers the activation of extrinsic apoptosis pathways (TRAIL, Fas-L and caspase-8, -9, -3), but it also suppresses the expression of the anti-apoptotic molecules Bcl-2 and Bcl-XL in a time-dependent manner.	erinacine S	28-39	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	116-121	
33900313-8	2021	Moreover, our data revealed that activation of the ROS-derived and AKT/FAK/PAK1 pathways is involved in the erinacine S-mediated transcriptional activation of Fas-L and TRAIL through H3K4 trimethylation on their promoters.	erinacine S	108-117	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	169-174