PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33973101-2 2021 Fatty acid synthase (FASN) is a key enzyme for the de novo synthesis of fatty acids, and monoacylglycerol esterase (MGLL) is an important metabolic enzyme that converts triglycerides into free fatty acids. Fatty Acids, Nonesterified 188-204 monoglyceride lipase Homo sapiens 89-114 20085702-3 2010 (2010) now demonstrate that an increase in monoacylglycerol lipase (MAGL) drives tumorigenesis through the lipolytic release and remodeling of free fatty acids. Fatty Acids, Nonesterified 143-159 monoglyceride lipase Homo sapiens 43-66 20085702-3 2010 (2010) now demonstrate that an increase in monoacylglycerol lipase (MAGL) drives tumorigenesis through the lipolytic release and remodeling of free fatty acids. Fatty Acids, Nonesterified 143-159 monoglyceride lipase Homo sapiens 68-72 33973101-2 2021 Fatty acid synthase (FASN) is a key enzyme for the de novo synthesis of fatty acids, and monoacylglycerol esterase (MGLL) is an important metabolic enzyme that converts triglycerides into free fatty acids. Fatty Acids, Nonesterified 188-204 monoglyceride lipase Homo sapiens 116-120 35522977-3 2022 MAGL expression is increased in invasive tumors, furnishing free fatty acids as pro-tumorigenic signals and for tumor cell growth. Fatty Acids, Nonesterified 60-76 monoglyceride lipase Homo sapiens 0-4 34823884-6 2022 This nanoplatform could utilize its reduction-responsive characteristic to rapidly release siRNA for efficient silencing of MGLL and CB-2, inducing concurrent suppression of free fatty acids (FFAs) generation in PAC cells and repolarization of TAMs into tumor-inhibiting M1-like phenotype. Fatty Acids, Nonesterified 174-190 monoglyceride lipase Homo sapiens 124-128 33632876-2 2021 An important enzyme for the endocannabinoid metabolism is the monoacylglycerol lipase (MAGL), which catalyzes the degradation of 2-arachidonoylglycerol (2-AG) to glycerol and free fatty acids. Fatty Acids, Nonesterified 175-191 monoglyceride lipase Homo sapiens 62-85 33632876-2 2021 An important enzyme for the endocannabinoid metabolism is the monoacylglycerol lipase (MAGL), which catalyzes the degradation of 2-arachidonoylglycerol (2-AG) to glycerol and free fatty acids. Fatty Acids, Nonesterified 175-191 monoglyceride lipase Homo sapiens 87-91 30059673-2 2018 Besides this role, MAGL has progressively acquired a growing importance as an integrative metabolic hub that controls not only the in vivo levels of 2-AG but also of other monoacylglycerides and, indirectly, the levels of free fatty acids derived from their hydrolysis as well as other lipids with pro-inflammatory or pro-tumorigenic effects, coming from the further metabolism of fatty acids. Fatty Acids, Nonesterified 222-238 monoglyceride lipase Homo sapiens 19-23 33085920-2 2021 Importantly, it was found that MAGL degradation of lipids in cancer cells enhances the availability of free fatty acids for new cellular membrane formation and pro-oncogenic lipid modulators. Fatty Acids, Nonesterified 103-119 monoglyceride lipase Homo sapiens 31-35 30034939-2 2018 Monoglyceride lipase (MGLL) is an important fatty acid metabolism enzyme, which converts monoacylglycerides to free fatty acids and glycerol. Fatty Acids, Nonesterified 111-127 monoglyceride lipase Homo sapiens 0-20 30034939-2 2018 Monoglyceride lipase (MGLL) is an important fatty acid metabolism enzyme, which converts monoacylglycerides to free fatty acids and glycerol. Fatty Acids, Nonesterified 111-127 monoglyceride lipase Homo sapiens 22-26 25120746-1 2014 Monoacylglycerol lipase (MAGL) is a serine hydrolase that hydrolyzes monoacylglycerides into free fatty acids and glycerol. Fatty Acids, Nonesterified 93-109 monoglyceride lipase Homo sapiens 0-23 25120746-1 2014 Monoacylglycerol lipase (MAGL) is a serine hydrolase that hydrolyzes monoacylglycerides into free fatty acids and glycerol. Fatty Acids, Nonesterified 93-109 monoglyceride lipase Homo sapiens 25-29